Message boards : News : New publication, new badges!
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Toni Volunteer moderator Project administrator Project developer Project tester Project scientist Send message Joined: 9 Dec 08 Posts: 1006 Credit: 5,068,599 RAC: 0 Level  Scientific publications    | |
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Dears! | |
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 [PUGLIA] kidkidkid3 Send message Joined: 23 Feb 11 Posts: 100 Credit: 1,343,101,646 RAC: 2,007,762 Level  Scientific publications  | |
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Hi, congratulations to all ! | |
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dskagcommunity Send message Joined: 28 Apr 11 Posts: 460 Credit: 840,395,994 RAC: 1,569,507 Level  Scientific publications  | |
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Yeay my first one :D | |
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I would like a link to this ranking ? Is it possible ? No, the rankings aren't on the web. Yeay my first one :D Here you'll find it. | |
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Retvari Zoltan Send message Joined: 20 Jan 09 Posts: 2355 Credit: 16,375,531,916 RAC: 3,695,757 Level  Scientific publications  | |
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Wow! | |
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Damaraland Send message Joined: 7 Nov 09 Posts: 152 Credit: 16,181,924 RAC: 0 Level  Scientific publications  | |
The signal is the recognition of a short peptide (pYEEI for friends) by a partner "plug", called the SH2 domain. This kind of signaling is in fact very common in cells for responding to all varieties of messages (for example in receptor kinases). After watching the video now I understand this statement perfectly! :o) Finally I've got my own personal Chuck Norris badge :) Congrats! Surprised? You get more credit in one day than me in one month! | |
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JLConawayII Send message Joined: 31 May 10 Posts: 48 Credit: 28,893,779 RAC: 0 Level  Scientific publications | |
Wow! Congratulations, but it doesn't make up for the extraordinarily unfortunate shape of that lysine badge. ^^ | |
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Retvari Zoltan Send message Joined: 20 Jan 09 Posts: 2355 Credit: 16,375,531,916 RAC: 3,695,757 Level Scientific publications | |
Congratulations, but it doesn't make up for the extraordinarily unfortunate shape of that lysine badge. ^^ :) See this video from 2:03 and 2:22 | |
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skgiven Volunteer moderator Volunteer tester  Send message Joined: 23 Apr 09 Posts: 3968 Credit: 1,995,359,260 RAC: 0 Level  Scientific publications | |
The signal is the recognition of a short peptide (pYEEI for friends) by a partner "plug", called the SH2 domain. This kind of signaling is in fact very common in cells for responding to all varieties of messages (for example in receptor kinases).
Just look at the surface changes (red) and you will appreciate how much the SH2 domain alters when pYEEI binds to the domain. Red and blue are commonly used to indicate hydrophobic and hydrophilic areas. ____________ FAQ's HOW TO: - Opt out of Beta Tests - Ask for Help | |
| ID: 24053 | Rating: 0 | rate:
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Red and blue are commonly used to indicate hydrophobic and hydrophilic areas. Good point. Indeed, red and blue often indicate hydrophilic (electrically charged) regions or hydrophobic (greasy) ones. However, in this very video red and blue indicate the fluctuation of the position of the atoms, that is for example, their vibration. So, if you pay attention, as the ligand (the skinny nervous fella) binds to his big buddy, goes from red to blue meaning that it reagidifies. And so happens in some degree for the big buddy (SH2 protein). It even partially hugs it from the left at 1:15... cheers | |
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Norman_RKN Send message Joined: 22 Dec 09 Posts: 16 Credit: 23,522,575 RAC: 0 Level Scientific publications | |
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congrats to all ! | |
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verlyol-belgium  Send message Joined: 9 Sep 08 Posts: 34 Credit: 24,784,154 RAC: 0 Level Scientific publications | |
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http://pubs.acs.org/toc/jctcce/0/0 | |
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CTAPbIi Send message Joined: 29 Aug 09 Posts: 175 Credit: 259,509,919 RAC: 0 Level  Scientific publications | |
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Thx :-) I hope this will help you, guys. | |
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Just realized i'm in top 25% of contributors in this one ( 346/3113 ) - cool :-) | |
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wiyosaya Send message Joined: 22 Nov 09 Posts: 114 Credit: 589,114,683 RAC: 0 Level  Scientific publications | |
Wow! Congrats!! I can just hear it now - "Chuck Norris Approved." LOL ____________ | |
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Betting Slip Send message Joined: 5 Jan 09 Posts: 670 Credit: 2,498,095,550 RAC: 0 Level  Scientific publications | |
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All well and good but as far as I can tell it doesn't bring us one step closer to understanding that universal mystery... | |
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Retvari Zoltan Send message Joined: 20 Jan 09 Posts: 2355 Credit: 16,375,531,916 RAC: 3,695,757 Level Scientific publications | |
All well and good but as far as I can tell it doesn't bring us one step closer to understanding that universal mystery... “Women are meant to be loved, not to be understood.” ― Oscar Wilde, Lord Arthur Savile's Crime and Other Stories | |
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dskagcommunity Send message Joined: 28 Apr 11 Posts: 460 Credit: 840,395,994 RAC: 1,569,507 Level Scientific publications | |
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=) =) =) | |
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Message boards : News : New publication, new badges!
