Advanced search

Message boards : News : New *xTRYP* WUs

Post to thread Subscribe Sort
Author Message
ignasi
Send message
Joined: 10 Apr 08
Posts: 254
Credit: 16,836,000
RAC: 0
Level
Pro
Scientific publications
watwatwatwatwatwatwatwatwatwatwatwat
Message 24476 - Posted: 18 Apr 2012 | 9:34:13 UTC

We are submitting a new batch of WUs (~1000) of our beloved trypsin and benzamidine system for a beautiful experiment in collaboration with a crystallographer.

It seems that these crystallographers and us may have got to similar conclusions on how trypsin and benzamidine like to interact. The nice thing is that we'd have got to the conclusions from VERY different approaches. They make crystals of trypsin/benzamidine and take pictures of their structures using a synchrotron and we make MD simulations of already solved structures and take many snapshots of what happened. And then we compare them.

If experimentalists (protein crystallographers in this case) are able to reproduce what we obtained from computer simulations or viceversa, it would be a beautiful (and necessary) validation of our methods.

Let's hope that all goes well.

Cheers!

ID: 24476 | Rating: 0 | rate: Rate + / Rate - Report as offensive    Reply Quote
Profile verlyol-belgium
Send message
Joined: 9 Sep 08
Posts: 34
Credit: 24,784,154
RAC: 0
Level
Pro
Scientific publications
watwatwatwatwatwatwatwatwatwatwatwatwat
Message 24545 - Posted: 22 Apr 2012 | 19:44:15 UTC

They are standard or long WU ?

ID: 24545 | Rating: 0 | rate: Rate + / Rate - Report as offensive    Reply Quote
Dagorath
Send message
Joined: 16 Mar 11
Posts: 509
Credit: 179,005,236
RAC: 0
Level
Ile
Scientific publications
watwatwatwatwatwatwatwatwatwatwatwatwatwat
Message 24551 - Posted: 23 Apr 2012 | 3:09:24 UTC - in response to Message 24476.

That is wonderful preliminary news! I'm sure we all hope it develops into the validation you seek.

ID: 24551 | Rating: 0 | rate: Rate + / Rate - Report as offensive    Reply Quote
ignasi
Send message
Joined: 10 Apr 08
Posts: 254
Credit: 16,836,000
RAC: 0
Level
Pro
Scientific publications
watwatwatwatwatwatwatwatwatwatwatwat
Message 24553 - Posted: 23 Apr 2012 | 9:50:13 UTC - in response to Message 24551.

They are standard or long WU ?

All long.

That is wonderful preliminary news! I'm sure we all hope it develops into the validation you seek.

Thanks!

ID: 24553 | Rating: 0 | rate: Rate + / Rate - Report as offensive    Reply Quote
Post to thread

Message boards : News : New *xTRYP* WUs

//